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The Neuropsychiatric Manifestation Of Wilsons Disease in a Tertiary Care Centre in India : Before and After Treatment

Date: 7 January 2018

MJP Online Code: MJP-02-01-17 

Section: Case Report

Authors: Saha A, Singh A, Kumar N

Institutions: Dept of Psychiatry, Armed Forces Medical College (AFMC), Pune-411040, Maharashtra, India

Keywords: Wilsons Disease, Neurological Condition, Copper, Choreoathetoid Movements, Peniciallmine, Benzodiazepines

Abstract: Wilsons disease is a neurological condition warranting immediate treatment. Being a rare genetic disorder it is characterized by excess copper stored in various body tissues, particularly the liver, brain, and corneas of the eyes. The disease is progressive and, if left untreated, it may cause liver (hepatic) disease, central nervous system dysfunction, and death. Psychiatric manifestations may coexist like irritability, abnormal movements, outburst in teenagers or people in their twenties. Early diagnosis and treatment may prevent serious long-term disability and life threatening complications. Treatment is aimed at reducing the amount of copper that has accumulated in the body and maintaining normal copper levels thereafter.

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